[Specific cutaneous manifestations in adult Tcell leukemia/lymphoma]

Adult T cell leukemia/lymphoma [ATLL] is an aggresive malignancy which may occur in human T lymphotropic virus [HTLVl] infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad In this descriptive study the demographic and clinical data of 23 patient suffering from ATLL who were admitted in hematology and dermatology departments of Ghaem Hospital, during 1995-2004 and had specific cutaneous lesions confirmed histopathologically with atypical lymphocytes in skin lesions, were recorded and analyzed. Eleven patients were male and 12 were female. The mean age of patients was 48.17 +/- 14.1 years. Birth places of over 85% of cases were north of Khorasan. The most common types of specific skin lesions were maculopapular rash in 11 cases [47.8%] and papular lesions in 4 cases [17.4%]. Other lesions included plaque, icthyosis like, erythroderma, tumor, and nodular lesions. In most of patients [56.5%] the skin lesions were generalized The most common type of specific skin lesions in ATLL was maculopapular rash especially with generalized distribution. Other types of specific skin lesions in order of frequency were papule, plaque, icthyosis like, nodule, tumor and erythroderma

Cutaneous manifestations of diabetes mellitus

Diabetes isa common disease with a variety of skin manifestations encountered by dermatologists, Skin and diabetes may be linked by association [e.g. necrobiosis lipoidica]; infections [bacterial, viral or fungal]; diabetic complications [e.g. neuropathic ulcers or treatment reactions]. The skin manifestations of diabetes affect up to two thirds of patients both type 1 and II diabetes mellitus. Cutanebus manifestations of diabetes occur because of the microvascular complications of diabetes, impaired wound healing, and other yet undetermined mechanisms. The aim of the present study was to look for major skin findings in patients with diabetes mellitus and to see their clinical correlation. All patients attending the diabetic clinic during a period of Qne year from July, 2002 to June, 2003 were examined in detail for cutaneous manifestations of the disease. 162 patients, 92 females and 70 males, were enrolled. The overall prevalence of cutaneous manifestations was 81.5% [80% in type I and 83.4% in type II diabetics]. These manifestations were microvascular [n73], neurological [n6 1], infections [n46], iatrogenic [n=7] and miscellaneous [n=184]. Cutaneous manifestations are quite frequent in both types of diabetics. A number of new findings were observed

Cutaneous manifestations of chronic liver disease

Hepatobiliary diseases are frequently associated with abnormalities of the skin, nails and hair. This study was undertaken to determine the cutaneous manifestations of chronic liver disease [CLD] and particular pattern associated with aetiology of disease. Patients suffering from chronic liver disease of any aetiology presenting to department of gastroenterology Hayatabad Medical Complex, Peshawar from 1st December 2004 to 30th April 2005 were enrolled in the study. All the relevant details regarding history and clinical examination were recorded on a specially designed pro forma. A total of fifty patients, 32 males and 18 females were included. Thirty [60%] patients were suffering from chronic hepatitis C virus infection, 14 patients were suffering from Chronic hepatitis B virus infection and 2 patients each were suffering from primary biliary cirrhosis and Wilson's disease. In two cases the aetiology could not be ascertained. Different manifestations included pigmentation [82%], Terry's nails [80%], xerosis and excoriations [72%], nonscarring hair loss from axilla and pubic region [64%], and spider naevi and palmar erythema [36%]. Lichen planus was seen in 4%, vitiligo and hepatocutaneous syndrome in [2%] of patients each. Cutaneous manifestations in chronic liver disease are non-specific and do not point towards specific aetiology. Physicians caring for patients with chronic liver disease should pay attention to its multisystemic nature

Manifestaçöes cutâneas produzidas pelo citomegalovírus (CMV) na síndrome de imunodeficiência adquirida (AIDS): consideraçöes anatomopatológicas - Relato de dois casos / Cutaneos manifestations produced by cytomegalovirus (CMV) in acquired ummunodeficiency syndrome (AIDS): anatomopathological considerations. Report of 2 cases

Os autores estudam as manifestaçöes cutâneas produzidas pelo CMV em necrópsias de pacientes com AIDS. Comparam a incidência das lesöes de pele, com a de outros órgäos, destacando a raridade desta infecçäo no tegumento, havendo particular comprometimento das estruturas dérmicas, com especial referência para as alteraçöes do endotélio vascular. A apresentaçäo de dois casos justifica-se pela raridade da condiçäo patológica e presta-se a chamar atençäo sobre a observaçäo de casos clínicos com o possível diagnóstico diferencial dentre as principais lesöes cutâneas virais, de tamanha importância na clínica dermatológica

Factores de riesgo de la Dermatitis en el area del panal / Risk factors for Dermatitis in diaper's area

Durante los meses de Enero a Marzo de 1988, el 33 por ciento de 275 ninos menores de 1 ano que demandaron servicios de cualquiera de los subprogramas de atencion materno infantil en el Centro de Salud del barrio Quirigua (Bogota) tenian dermatitis por el panal. Esto motivo que entre Marzo y Mayo del mismo ano se encuestaran 105 madres o ciudadores primarios de ninos con panalitis para establecer que cuidados higienicos pueden ser factores de riesgo. La mayor incidencia de panalitis estuvo en los ninos de 4 meses (16 por ciento ) seguidos de los ninos de 7 meses (14 por ciento ), edades en las cuales se hacen importantes cambios de dieta. Tanto los varones como las mujeres se vieron afectados en proporciones similares (49.50 por ciento y 50.5 por ciento ). El 78 por ciento fueron cuidados por la madre y el 10 por ciento por las hermanas o las tias. El 53 por ciento solo banan al bebe cuando hace deposicion, el 27 por ciento lo banan con cada cambio de panal y el 20 por ciento lo banan una vez al dia. El 49 por ciento aplican crema, el 20 por ciento talco y el 17 por ciento maizena. El 20 por ciento limpia los genitales del nino con agua, el 66 por ciento utiliza agua y jabon para bebe y el 13 por ciento emplea jabon perfumado. El 69 por ciento utiliza panales de tela y el 27 por ciento los alterna con panales desechables. El 77 por ciento le cambia el panal cuando lo siente mojado, el 13 por ciento cuando el nino hace deposicion y el 10 por ciento a horas determinadas. El 66 por ciento lava los panales solos, el 27 por ciento con el resto de la ropa del bebe y el 7.8 por ciento con la ropa de la familia